How the brain processes visual information in different states of alertness

Cellular Mechanisms of State-Dependent Processing in Visual Cortex

NIH-funded research University of Connecticut Storrs · NIH-10899669

This study looks at how the brains of rabbits handle what they see when they're awake, drowsy, or lightly sleeping, to help us understand how different levels of alertness affect our vision.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Connecticut Storrs NIH-funded
Lab location1 site (Storrs-Mansfield, United States)
Project IDNIH-10899669 on NIH RePORTER

What this research studies

This research investigates how the brain's visual cortex processes visual information when animals are in various states of alertness, including drowsiness and light sleep. By studying rabbits, which can naturally transition between these states, researchers will record the activity of neurons in the visual cortex and thalamus. The goal is to understand how these different states affect the way visual information is received and processed. This could provide insights into the cellular mechanisms that underlie visual perception beyond just awake and attentive states.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would include individuals with cognitive disorders affecting visual perception or attention.

Not a fit: Patients with stable cognitive function and no visual processing issues may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of visual processing in humans, potentially leading to better treatments for cognitive disorders related to attention and perception.

How similar studies have performed: While there has been research on visual processing in awake states, this approach of examining transitions between alert and nonalert states in a naturalistic setting is relatively novel.

Where this research is happening

Storrs-Mansfield, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.