How the brain preserves information from multiple sights and sounds

Information Preservation in Neural Codes

NIH-funded research Duke University · NIH-11299537

This project looks at how groups of brain cells keep information about several sights and sounds at once to help people with attention and auditory processing challenges.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-11299537 on NIH RePORTER

What this research studies

I want to understand how my brain can remember and respond to many things happening at once. The researchers study patterns of activity in groups of neurons that can switch between representing different stimuli, focusing on brain hubs involved in hearing (inferior colliculus) and attention/movement (superior colliculus). They will examine how these fluctuating activity patterns are coordinated across sensory and motor areas and during tasks that require preserving information versus selecting a single item. The team uses detailed neural recordings and behavioral tasks to link these brain activity patterns to how well information is kept or selected.

Who could benefit from this research

Good fit: People with attention difficulties, autism spectrum conditions, or complaints of central auditory processing who are willing to participate in research at Duke would be the most relevant candidates.

Not a fit: Those without attention or auditory processing concerns or people seeking immediate clinical treatment are unlikely to get direct benefit from this basic neuroscience project.

Why it matters

Potential benefit: If successful, this work could reveal brain mechanisms behind attention and auditory processing that help guide future tests or treatments for ADHD, autism, and central auditory processing disorder.

How similar studies have performed: Previous neural recording studies have identified switching activity patterns and roles for the inferior and superior colliculus, but applying these findings to how the brain preserves competing information is a newer direction.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Attention Deficit DisorderAutistic DisorderCentral Auditory Processing Disorder
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.