How the brain organizes memories and experiences
The laminar organization of 'index' versus 'attribute' coding in neocortex
['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA-IRVINE · NIH-11051205
This study is looking at how our brains store and remember experiences, especially how different parts of the brain work together to help us recall memories, which could be helpful for understanding memory issues in people with autism.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA-IRVINE (nih funded) |
| Locations | 1 site (IRVINE, UNITED STATES) |
| Trial ID | NIH-11051205 on ClinicalTrials.gov |
What this research studies
This research investigates how the brain encodes and retrieves memories by examining the organization of neural circuits in the neocortex. It focuses on understanding how different layers of the neocortex represent the attributes of experiences and the contexts in which they occur. By studying the connections between these layers, the research aims to uncover the mechanisms that allow the brain to recall memories and predict behaviors. This could provide insights into how memory processing works, particularly in relation to conditions like autism spectrum disorder.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals diagnosed with autism spectrum disorder or those experiencing memory processing difficulties.
Not a fit: Patients without memory processing issues or those not diagnosed with autism spectrum disorder may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment strategies for memory-related conditions, including autism spectrum disorder.
How similar studies have performed: Other research has shown success in understanding memory processing through neural circuit analysis, suggesting that this approach could yield valuable insights.
Where this research is happening
IRVINE, UNITED STATES
- UNIVERSITY OF CALIFORNIA-IRVINE — IRVINE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MCNAUGHTON, BRUCE L — UNIVERSITY OF CALIFORNIA-IRVINE
- Study coordinator: MCNAUGHTON, BRUCE L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: autism spectral disorder, autism spectrum disorder