How the brain forms memories during everyday experiences

Hippocampal-Neocortical Interactions During Naturalistic Learning

NIH-funded research New York University School of Medicine · NIH-11051147

This study is looking at how our brains create and organize memories while we go about our daily lives, especially focusing on how two important brain areas work together, and it could help us understand memory problems in conditions like Alzheimer's disease.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York University School of Medicine NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11051147 on NIH RePORTER

What this research studies

This research investigates how the brain processes and organizes memories during daily activities, focusing on the interactions between the hippocampus and neocortex. By examining brain activity during key moments of memory formation, the study aims to understand how our brains segment experiences into meaningful memories. Using advanced neuroimaging techniques, researchers will measure specific brain wave patterns that occur when we form memories, particularly during transitions in experiences. This work could provide insights into memory impairments associated with conditions like Alzheimer's disease.

Who could benefit from this research

Good fit: Ideal candidates for this research include individuals with memory impairments due to conditions such as Alzheimer's disease or traumatic brain injury.

Not a fit: Patients with intact memory function or those not experiencing cognitive decline may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for enhancing memory function in patients with neurological disorders.

How similar studies have performed: Previous research has shown promising results in understanding memory formation through similar neuroimaging approaches, indicating that this line of inquiry is both relevant and potentially impactful.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndromeAlzheimer's Disease
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.