How the brain forms memories during everyday experiences
Official title: Hippocampal-Neocortical Interactions During Naturalistic Learning
Funded at New York University School of Medicine · NIH-11051147 · Data updated 2026-11-12
This study is looking at how our brains create and organize memories while we go about our daily lives, especially focusing on how two important brain areas work together, and it could help us understand memory problems in conditions like Alzheimer's disease.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | April 10, 2023 |
| Project end | March 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $576,488 |
| NIH project number | 5R01NS127954-03 |
| Project ID | NIH-11051147 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals with memory impairments due to conditions such as Alzheimer's disease or traumatic brain injury.
✕Less likely to help
Patients with intact memory function or those not experiencing cognitive decline may not benefit from this research.
What this research studies
This research investigates how the brain processes and organizes memories during daily activities, focusing on the interactions between the hippocampus and neocortex. By examining brain activity during key moments of memory formation, the study aims to understand how our brains segment experiences into meaningful memories. Using advanced neuroimaging techniques, researchers will measure specific brain wave patterns that occur when we form memories, particularly during transitions in experiences. This work could provide insights into memory impairments associated with conditions like Alzheimer's disease.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for enhancing memory function in patients with neurological disorders.
How similar studies have gone: Previous research has shown promising results in understanding memory formation through similar neuroimaging approaches, indicating that this line of inquiry is both relevant and potentially impactful.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Liu, Anli a — New York University School of Medicine
- Study coordinator: Liu, Anli a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.