How the brain decides between different ways to learn from experiences

Circuit mechanisms of arbitration between distinct reinforcement learning systems

NIH-funded research New York University · NIH-11035108

This study is looking at how our brains make decisions based on what we've learned, especially when we're in new situations, and it aims to help us understand how different parts of the brain work together to guide our choices, which could be useful for everyone, including those with learning challenges.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionNew York University NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11035108 on NIH RePORTER

What this research studies

This research investigates how the brain uses different systems to make decisions based on experiences, particularly in new environments. It focuses on understanding the mechanisms behind 'model-based' reasoning, where the brain creates an internal model to predict outcomes, versus 'model-free' learning, which relies solely on past experiences. By studying the lateral orbitofrontal cortex and its role in decision-making, the research aims to uncover how these systems interact and influence behavior. This could provide insights into cognitive processes that affect learning and decision-making in both animals and humans.

Who could benefit from this research

Good fit: Ideal candidates for this research would include individuals with cognitive impairments or those interested in understanding decision-making processes.

Not a fit: Patients without cognitive impairments or those not engaged in decision-making tasks may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of decision-making processes, potentially leading to improved strategies for addressing cognitive disorders.

How similar studies have performed: Previous research has shown promising results in understanding decision-making processes through similar approaches, indicating a strong foundation for this investigation.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.