How the brain controls memory and decision-making under stress
Integrated mechanisms for orbitofrontal cortical control of memory and choice
This study looks at how a part of the brain helps us remember and make choices, especially when we're feeling stressed, and it aims to find ways to improve our decision-making and memory during tough times.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project ID | NIH-10987005 on NIH RePORTER |
What this research studies
This research investigates how the brain's orbitofrontal cortex helps us remember and choose actions based on expected outcomes, especially when under stress. It focuses on understanding how certain neurons in this brain region encode and retrieve memories that guide our behavior. By studying the connections between different brain areas, the research aims to uncover the mechanisms that lead to compulsive behaviors and poor decision-making. The findings could help develop strategies to improve memory and decision-making in stressful situations.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing stress-related decision-making issues or compulsive behaviors.
Not a fit: Patients who do not experience stress-related decision-making issues or compulsive behaviors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new treatments for conditions related to compulsive behaviors and decision-making difficulties.
How similar studies have performed: Previous research has shown promising results in understanding brain mechanisms related to memory and decision-making, suggesting that this approach could yield valuable insights.
Where this research is happening
Atlanta, United States
- Emory University — Atlanta, United States (Active)
Researchers
- Principal investigator: Gourley, Shannon Leigh — Emory University
- Study coordinator: Gourley, Shannon Leigh
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.