How the brain controls information seeking behavior
Mechanisms of Information Seeking in the Primate Brain
['FUNDING_R01'] · WASHINGTON UNIVERSITY · NIH-11050439
This study looks at how certain parts of the brain help us stay motivated and make decisions by figuring out what information we need to feel more certain, and it aims to help everyone understand how these brain processes work, especially for those who might struggle with decision-making.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | WASHINGTON UNIVERSITY (nih funded) |
| Locations | 1 site (SAINT LOUIS, UNITED STATES) |
| Trial ID | NIH-11050439 on ClinicalTrials.gov |
What this research studies
This research investigates the brain systems that influence our motivation and decision-making by focusing on how we seek information to reduce uncertainty. It explores the connections between specific brain areas, such as the anterior cingulate cortex and basal ganglia, to understand how they encode the value of information and drive behavior. By studying these mechanisms in primates, the research aims to uncover how the thalamus mediates the computations in the prefrontal cortex that regulate information seeking. This could provide insights into the underlying processes that affect decision-making in both healthy individuals and those with disorders.
Who could benefit from this research
Good fit: Ideal candidates for this research include individuals with conditions affecting decision-making and motivation, such as autism spectrum disorder or anxiety disorders.
Not a fit: Patients with neurological conditions unrelated to decision-making or information processing may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of conditions related to decision-making and motivation, such as anxiety and autism.
How similar studies have performed: Other research has shown success in understanding brain mechanisms related to decision-making, suggesting that this approach could yield valuable insights.
Where this research is happening
SAINT LOUIS, UNITED STATES
- WASHINGTON UNIVERSITY — SAINT LOUIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: MONOSOV, ILYA E. — WASHINGTON UNIVERSITY
- Study coordinator: MONOSOV, ILYA E.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Affective Disorders, Autistic Disorder