NIH-funded research R01 grant

How the brain builds social connections

Official title: Characterizing the neural mechanisms of social connection

Funded at Rutgers the State Univ of Nj Newark · NIH-11261093 · Data updated 2026-11-12

This work looks at how brain circuits create feelings of connection and how that might help people who feel isolated or struggle with substance use.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRutgers the State Univ of Nj Newark
NIH-funded
Lab location1 site (Newark, United States)
Project startApril 15, 2022
Project endJanuary 31, 2027
Funding year2026
Award (this year)$494,025
NIH project number5R01DA053311-05
Project IDNIH-11261093 on NIH RePORTER

Who could benefit from this research

Could help

Adults who feel socially isolated or who are struggling with substance use or maladaptive coping related to loneliness would be most relevant.

Less likely to help

People without issues of social isolation or substance-related coping, or whose conditions require strictly medical interventions unrelated to social behavior, may not see direct benefit.

What this research studies

From a patient's point of view, researchers will examine the brain circuits that make social interactions feel rewarding and help people form bonds. They will use controlled social interaction experiments and neural measurements (including animal models that inform human biology) to trace how shared understanding between people emerges. The team will link those neural signals to behaviors tied to loneliness and substance use to see how social rewards can steer choices. Findings will be used to guide new ways to help people build healthier social ties and reduce harmful coping like drug or alcohol use.

Why it matters

Potential benefit: If successful, this work could lead to new treatments or therapies that help people form healthier social connections and reduce substance-related coping.

How similar studies have gone: Animal studies already suggest social opportunity can reduce substance use, but translating the specific brain mechanisms to people is still relatively new.

Where this research is happening

  • Rutgers the State Univ of Nj Newark
    Newark, United States
    Active

Researchers

  • Principal investigator: Delgado, Mauricio R. — Rutgers the State Univ of Nj Newark
  • Study coordinator: Delgado, Mauricio R.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.