NIH-funded research R01 grant

How the brain adapts to visual experiences in adults

Official title: Experience-dependent plasticity of circuit dynamics

Funded at Yale University · NIH-10995301 · Data updated 2026-11-12

This study is looking at how the brain can change and improve when we see different things, which could help people with vision problems like amblyopia and lead to new ways to recover from visual injuries.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startJanuary 1, 2024
Project endDecember 31, 2027
Funding year2025
Award (this year)$522,377
NIH project number5R01EY035127-02
Project IDNIH-10995301 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation or benefit from this research are adults aged 21 and older who have visual impairments or conditions affecting their visual processing.

Less likely to help

Patients with stable visual function and no history of visual impairments may not receive any benefit from this research.

What this research studies

This research investigates how the adult brain's neural circuits can adapt and change in response to visual experiences. By examining the role of specific inhibitory neurons in the visual cortex, the study aims to understand how different types of visual stimuli can enhance brain function. The researchers will use advanced imaging techniques to observe these changes in real-time, potentially leading to new therapies for conditions like amblyopia and other visual impairments. The findings could provide insights into how to harness brain plasticity for rehabilitation after injury or developmental issues.

Why it matters

Potential benefit: If successful, this research could lead to innovative treatments for visual disorders and improve recovery strategies for brain injuries.

How similar studies have gone: Previous research has shown promising results in understanding neural plasticity in younger populations, but this approach in adults is relatively novel and untested.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Cardin, Jessica a — Yale University
  • Study coordinator: Cardin, Jessica a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.