How the brain adapts during learning processes

Plasticity of cortical networks during learning

['FUNDING_FELLOWSHIP'] · YALE UNIVERSITY · NIH-11238609

This study looks at how the brain changes when mice learn to associate what they see with rewards, helping us understand how learning affects brain connections over time.

Quick facts

Phase['FUNDING_FELLOWSHIP']
Study typeNih_funding
SexAll
SponsorYALE UNIVERSITY (nih funded)
Locations1 site (NEW HAVEN, UNITED STATES)
Trial IDNIH-11238609 on ClinicalTrials.gov

What this research studies

This research investigates how the primary visual cortex (V1) in the brain changes in response to different stages of visual associative learning. By using a specially designed task that separates early and late learning phases, the study aims to understand how visual stimuli paired with rewards affect brain activity. The researchers will employ advanced imaging techniques to observe changes in neuron activity and connectivity in the mouse brain during these learning phases. This approach could reveal important insights into how learning influences brain plasticity.

Who could benefit from this research

Good fit: Ideal candidates for this research would be individuals interested in the mechanisms of learning and memory, particularly those affected by learning disorders.

Not a fit: Patients with conditions unrelated to learning or memory, such as purely physical ailments, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance our understanding of learning processes and potentially lead to new treatments for conditions related to learning and memory.

How similar studies have performed: Previous research has shown promising results in understanding brain plasticity during learning, suggesting that this approach could yield valuable insights.

Where this research is happening

NEW HAVEN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: addictive disorder

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.