How the body's internal clock affects stress responses and heart health
Role of the circadian rhythm on endocannabinoid response to an acute stress
['FUNDING_CAREER'] · OREGON HEALTH & SCIENCE UNIVERSITY · NIH-11005761
This study looks at how our body's internal clock affects the way we respond to stress and how it might impact heart health, especially for people who work night shifts or have unusual schedules.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | OREGON HEALTH & SCIENCE UNIVERSITY (nih funded) |
| Locations | 1 site (PORTLAND, UNITED STATES) |
| Trial ID | NIH-11005761 on ClinicalTrials.gov |
What this research studies
This research investigates how the body's circadian rhythm influences the response of endocannabinoids, which are natural compounds that help regulate stress and cardiovascular function, during acute stress events. The study will examine how these responses vary depending on the time of day and how they relate to emotional and cardiovascular reactions. By understanding these mechanisms, the research aims to shed light on the risks of cardiovascular disease, particularly in individuals who work night shifts or have irregular schedules.
Who could benefit from this research
Good fit: Ideal candidates for this research include adults over 21 who experience acute stress, particularly those who work night or rotating shifts.
Not a fit: Patients who do not experience acute stress or those under 21 years old may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved strategies for managing stress and reducing cardiovascular risks, especially for shift workers.
How similar studies have performed: Previous research has shown promising results in understanding the role of circadian rhythms in stress responses, suggesting that this approach could yield valuable insights.
Where this research is happening
PORTLAND, UNITED STATES
- OREGON HEALTH & SCIENCE UNIVERSITY — PORTLAND, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BOWLES, NICOLE P — OREGON HEALTH & SCIENCE UNIVERSITY
- Study coordinator: BOWLES, NICOLE P
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.