How the body's internal clock affects fat cell behavior
Circadian Regulation of In Vitro Differentiated Adipocytes
This study is looking at how our body's internal clock affects fat cells and their behavior throughout the day, which could help us understand more about obesity and metabolism for people who are interested in these health issues.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Dartmouth College NIH-funded |
| Lab location | 1 site (Hanover, United States) |
| Project ID | NIH-10991040 on NIH RePORTER |
What this research studies
This research investigates the role of circadian rhythms, or the body's internal clock, in the biology of fat cells (adipocytes). By studying fat cells grown in the lab, the researchers aim to understand how these cells change their behavior based on time of day, particularly in relation to energy use and heat production. The study will involve analyzing gene expression patterns in these cells over a period of three days to uncover how their functions are influenced by circadian rhythms. This could provide insights into how obesity and metabolic disorders are linked to our biological clocks.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals who are struggling with obesity or metabolic dysregulation.
Not a fit: Patients who do not have issues related to obesity or metabolic disorders may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for treating obesity and related metabolic disorders by targeting the circadian regulation of fat cells.
How similar studies have performed: While the specific approach of linking circadian rhythms to adipocyte biology is relatively novel, there is growing evidence that circadian regulation plays a significant role in metabolic health.
Where this research is happening
Hanover, United States
- Dartmouth College — Hanover, United States (Active)
Researchers
- Principal investigator: Frederick, Armina-Lyn M — Dartmouth College
- Study coordinator: Frederick, Armina-Lyn M
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.