How the body controls energy intake after weight loss
Official title: Physiological regulation of energy intake at meals following weight loss
Funded at University of Colorado Denver · NIH-11070802 · Data updated 2026-11-12
This study is looking at how our bodies control how much we eat after we've lost weight, and it's for people who have recently shed some pounds; we'll be measuring things like gut hormones and hunger responses to see what affects our appetite and energy levels during meals.
Quick facts
| Grant type | Fellowship grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Colorado Denver NIH-funded |
| Lab location | 1 site (Aurora, UNITED STATES) |
| Project start | January 1, 2025 |
| Project end | December 31, 2025 |
| Funding year | 2025 |
| Award (this year) | $75,520 |
| NIH project number | 1F32DK139699-01A1 |
| Project ID | NIH-11070802 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who have recently lost weight and are struggling to maintain their weight loss.
✕Less likely to help
Patients who are not currently experiencing weight loss or those with eating disorders may not benefit from this research.
What this research studies
This research investigates how the body regulates the amount of food we eat during meals after losing weight. It focuses on understanding the physiological mechanisms that lead to increased energy intake, which can contribute to weight regain. By analyzing data from previous studies, the research aims to identify factors that influence appetite and energy balance in individuals who have lost weight. Participants will be involved in measuring gut hormones and appetite responses to different meal timings.
Why it matters
Potential benefit: If successful, this research could help develop strategies to prevent weight regain after dieting, leading to more effective long-term weight management.
How similar studies have gone: Previous research has shown promising results in understanding appetite regulation and energy balance, suggesting that this approach could yield valuable insights.
Where this research is happening
-
University of Colorado Denver
Aurora, United States Active
Researchers
- Principal investigator: Ezpeleta, Mark — University of Colorado Denver
- Study coordinator: Ezpeleta, Mark
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.