How the aorta changes after endovascular repair with stent-grafts
Official title: Biomechanics and Hemodynamics of Human Aorta with Remodeling after Endovascular Repair
Funded at California State University Long Beach · NIH-11177887 · Data updated 2026-11-12
This project looks at how using multiple stent-grafts in less-invasive aortic repair changes aortic shape and blood flow in people with type B aortic dissection.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | California State University Long Beach NIH-funded |
| Lab location | 1 site (Long Beach, United States) |
| Project start | September 1, 2024 |
| Project end | July 31, 2028 |
| Funding year | 2025 |
| Award (this year) | $188,125 |
| NIH project number | 5R16HL178878-02 |
| Project ID | NIH-11177887 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with type B aortic dissection who are undergoing or have undergone thoracic endovascular aortic repair, especially those who received or may need multiple stent-grafts, are the most relevant candidates.
✕Less likely to help
People without TEVAR (for example those with type A dissection, isolated non-treated aneurysms, or who are not getting CT follow-up) are unlikely to benefit directly from this work.
What this research studies
If you have a type B aortic dissection treated with thoracic endovascular aortic repair (TEVAR), this work follows how your aorta remodels over time using routine CT scans and imaging measurements. The team will combine 3-D imaging, measurements of aortic diameter and lumen volume, and blood-flow (hemodynamic) and biomechanics analysis to understand effects of placing two or more endografts. Researchers will compare pre- and post-repair images and use models to link device placement with changes in wall stress and flow that may predict problems. The project focuses on long-term follow-up to find imaging features beyond simple size measures that better track risk after TEVAR.
Why it matters
Potential benefit: If successful, the findings could help doctors plan repairs and follow-up so patients have lower risks of complications like rupture or impaired organ blood flow.
How similar studies have gone: Previous imaging and flow-modeling work has informed TEVAR care, but the long-term biomechanical and hemodynamic effects of using multiple endografts are still not well characterized.
Where this research is happening
-
California State University Long Beach
Long Beach, United States Active
Researchers
- Principal investigator: Suh, Ga-Young Kelly — California State University Long Beach
- Study coordinator: Suh, Ga-Young Kelly
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.