NIH-funded research R01 grant

How teens' sleep patterns affect tiredness and daily functioning

Official title: The role of variability in sleep domains on adolescent fatigue and functioning

Funded at Case Western Reserve University · NIH-11305209 · Data updated 2026-11-12

This project looks at how changes in sleep duration and timing relate to tiredness, daytime sleepiness, and everyday functioning in early adolescents, especially in families facing social or neighborhood challenges.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionCase Western Reserve University
NIH-funded
Lab location1 site (Cleveland, United States)
Project startMay 1, 2021
Project endJanuary 31, 2027
Funding year2026
Award (this year)$615,314
NIH project number5R01HD104601-05
Project IDNIH-11305209 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are early adolescents (and their caregivers), especially from families experiencing household or neighborhood challenges that affect sleep.

Less likely to help

Children outside the early adolescent age range or teens without sleep problems may not directly benefit from this work.

What this research studies

You would be asked to share information about your teen’s sleep, tiredness, and daily activities while researchers measure different sleep features such as how long and when your teen sleeps. The team will examine fatigue and daytime sleepiness separately and track how these link to sleep variability like inconsistent bedtimes or shorter sleep. They will also collect information about household routines, socioeconomic circumstances, and neighborhood conditions to see how these social-environmental factors shape sleep and fatigue. The focus is on early adolescence, a time when sleep patterns change and can affect school, mood, and driving safety.

Why it matters

Potential benefit: If successful, the findings could help families and doctors target sleep-related factors to reduce teen fatigue and improve daily functioning.

How similar studies have gone: Previous research links poor sleep to teen fatigue, but separating sleep variability from daytime sleepiness and testing multi-level social influences is a newer and less-tested approach.

Where this research is happening

  • Case Western Reserve University
    Cleveland, United States
    Active

Researchers

  • Principal investigator: Spilsbury, James — Case Western Reserve University
  • Study coordinator: Spilsbury, James

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.