How systemic racism affects cognitive aging in patients with end-stage renal disease
Official title: Structural Racism, Resilience, and Premature Cognitive Aging in End-stage Renal Disease
Funded at New York University School of Medicine · NIH-11080355 · Data updated 2026-11-12
This study is looking at how racism affects brain health in Black patients with severe kidney disease, aiming to understand why some people experience faster cognitive decline and how others manage to stay resilient, so we can find better ways to support their health.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | New York University School of Medicine NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | July 15, 2022 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $789,298 |
| NIH project number | 5R01AG077888-04 |
| Project ID | NIH-11080355 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are Black adults aged 21 and older who are living with end-stage renal disease.
✕Less likely to help
Patients who do not have end-stage renal disease or those outside the age range of 21 and older may not benefit from this research.
What this research studies
This research investigates the relationship between systemic racism and cognitive aging in patients with end-stage renal disease (ESRD). It focuses on understanding how structural, institutional, and interpersonal racism contributes to cognitive impairment, particularly in Black ESRD patients. The study aims to identify mechanisms that lead to premature cognitive aging and resilience among these patients, using a comprehensive approach that includes measuring the impact of racism on health outcomes. By analyzing data from various age groups, the research seeks to inform interventions and policies that could mitigate the effects of cognitive decline associated with ESRD.
Why it matters
Potential benefit: If successful, this research could lead to targeted interventions that improve cognitive health and quality of life for Black patients with end-stage renal disease.
How similar studies have gone: While the specific focus on systemic racism and cognitive aging in ESRD patients is novel, related research has shown that addressing health disparities can lead to improved outcomes in other populations.
Where this research is happening
-
New York University School of Medicine
New York, United States Active
Researchers
- Principal investigator: Mcadams Demarco, Mara a. — New York University School of Medicine
- Study coordinator: Mcadams Demarco, Mara a.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.