How surgery affects patients using medications for opioid use disorder
Official title: The Impact of Surgery on Outcomes for Patients taking Medications for Opioid Use Disorder
Funded at University of Michigan at Ann Arbor · NIH-10930927 · Data updated 2026-11-12
This study is looking at how medications for opioid use disorder, like buprenorphine and methadone, affect pain management and recovery for patients after surgery, so we can find better ways to help them feel comfortable and heal.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | September 30, 2023 |
| Project end | June 30, 2028 |
| Funding year | 2024 |
| Award (this year) | $655,820 |
| NIH project number | 5R01DA057943-02 |
| Project ID | NIH-10930927 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with opioid use disorder who are currently receiving medications like buprenorphine, methadone, or naltrexone and are scheduled for surgical procedures.
✕Less likely to help
Patients who are not on medications for opioid use disorder or those who do not require surgical intervention may not benefit from this research.
What this research studies
This research investigates the impact of surgical procedures on patients who are taking medications for opioid use disorder, such as buprenorphine, methadone, and naltrexone. It aims to understand how these medications influence pain management and recovery after surgery, particularly focusing on the challenges faced by patients who develop tolerance to opioid pain relievers. The study will analyze outcomes related to pain management and opioid use in a surgical context, providing evidence to guide clinical practices and improve patient care. By examining these factors, the research seeks to clarify the best practices for managing acute pain in patients undergoing surgery while on these medications.
Why it matters
Potential benefit: If successful, this research could lead to improved pain management strategies for patients with opioid use disorder undergoing surgery, enhancing their recovery and overall health outcomes.
How similar studies have gone: Previous research has indicated the need for more rigorous studies in this area, suggesting that while some guidelines exist, there is a lack of high-quality evidence to support them, making this research both necessary and potentially groundbreaking.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Nguyen, Thuy Dieu — University of Michigan at Ann Arbor
- Study coordinator: Nguyen, Thuy Dieu
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.