How surface-associated microbes adapt and evolve in dense populations
Evolutionary adaptation of dense microbial populations to range expansion
['FUNDING_FELLOWSHIP'] · CORNELL UNIVERSITY · NIH-10913345
This study looks at how a type of yeast changes and grows better on surfaces, which could help us understand how tiny organisms adapt and thrive in crowded places, and this information might be useful for improving health and technology.
Quick facts
| Phase | ['FUNDING_FELLOWSHIP'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | CORNELL UNIVERSITY (nih funded) |
| Locations | 1 site (ITHACA, UNITED STATES) |
| Trial ID | NIH-10913345 on ClinicalTrials.gov |
What this research studies
This research investigates how microbial populations, specifically budding yeast, adapt to grow more efficiently on surfaces. By conducting experiments that simulate range expansion, the researchers observe changes in cell shape and growth patterns, which may enhance their ability to thrive in dense environments. The study aims to uncover the genetic changes that lead to these adaptations and how they influence interactions among cells. This knowledge could provide insights into the evolutionary dynamics of microbes that are important for human health and technology.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with conditions influenced by microbial populations, such as infections or those undergoing treatments that involve microbial therapies.
Not a fit: Patients with conditions unrelated to microbial dynamics or those not affected by microbial therapies may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding of microbial behavior that may enhance biotechnological applications and health outcomes.
How similar studies have performed: Other research has shown success in understanding microbial evolution and adaptation, suggesting that this approach could yield valuable insights.
Where this research is happening
ITHACA, UNITED STATES
- CORNELL UNIVERSITY — ITHACA, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RANDOLPH, KATIE ELAINE — CORNELL UNIVERSITY
- Study coordinator: RANDOLPH, KATIE ELAINE
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.