How structural racism and discrimination affect breast cancer survival

Social Genomic Mechanisms Linking Structural Racism, Perceived Discrimination, and Breast Cancer Survival

NIH-funded research Sloan-Kettering Inst Can Research · NIH-10860344

This study is looking at how experiences of racism and discrimination might affect breast cancer survival for women living in neighborhoods that have faced historical unfair treatment, and it hopes to find out how these social factors can influence their health and immune responses.

Quick facts

Grant typeR37 grant
Study typeNIH-funded research
Funding institutionSloan-Kettering Inst Can Research NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-10860344 on NIH RePORTER

What this research studies

This research investigates the impact of structural racism and perceived discrimination on breast cancer survival rates among women living in historically redlined neighborhoods. It aims to uncover the biological mechanisms that may contribute to shorter recurrence-free survival in these populations, despite receiving guideline-concordant treatments. By analyzing blood and tissue samples from a diverse cohort, the study will explore how social factors influence immune responses and cancer biology. The findings could lead to a better understanding of health disparities and inform targeted interventions.

Who could benefit from this research

Good fit: Ideal candidates for this research are women diagnosed with breast cancer who reside in historically redlined neighborhoods and have experienced perceived discrimination.

Not a fit: Patients who do not have breast cancer or who live outside of historically redlined neighborhoods may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment strategies and support systems for breast cancer patients affected by structural racism and discrimination.

How similar studies have performed: Other research has indicated that social determinants of health can significantly impact cancer outcomes, suggesting that this approach may yield valuable insights.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.