How stroke and botulinum toxin affect ankle movement during walking

Functional implications of stroke and Botulinum Neurotoxin on ankle stiffness and viscosity during gait

NIH-funded research University of Michigan at Ann Arbor · NIH-11063970

This study is looking at how stroke and botulinum injections affect the stiffness and movement of your ankle, which are important for walking, to help doctors find better ways to support stroke survivors like you.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor NIH-funded
Lab location1 site (Ann Arbor, United States)
Project IDNIH-11063970 on NIH RePORTER

What this research studies

This research investigates how stroke and botulinum neurotoxin injections impact ankle stiffness and viscosity, which are crucial for walking. It aims to provide a deeper understanding of the mechanical properties of the ankle joint that influence mobility after a stroke. By using advanced assessment techniques, the study seeks to uncover internal changes in joint mechanics that traditional evaluations may overlook. This could lead to improved clinical decision-making and tailored interventions for stroke survivors.

Who could benefit from this research

Good fit: Ideal candidates for this research are stroke survivors experiencing gait impairments, particularly those with ankle stiffness issues.

Not a fit: Patients who have not experienced a stroke or do not have gait impairments may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could enhance rehabilitation strategies for stroke patients, leading to better mobility and quality of life.

How similar studies have performed: Previous research has shown promising results in understanding gait mechanics post-stroke, but this specific approach focusing on internal joint properties is relatively novel.

Where this research is happening

Ann Arbor, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.