How stress-related high blood sugar affects tuberculosis treatment and diabetes risk
Official title: Immunometabolic impact of stress hyperglycemia on tuberculosis treatment outcomes and risk of diabetes mellitus
Funded at Emory University · NIH-11042238 · Data updated 2026-11-12
This study is looking at how stress-related high blood sugar affects the treatment of tuberculosis (TB) and whether it increases the chances of developing diabetes afterward, specifically for patients in places like Georgia where both conditions are common.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | March 4, 2021 |
| Project end | February 28, 2026 |
| Funding year | 2025 |
| Award (this year) | $749,831 |
| NIH project number | 5R01AI153152-05 |
| Project ID | NIH-11042238 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with tuberculosis, particularly those experiencing stress hyperglycemia.
✕Less likely to help
Patients without tuberculosis or those who do not experience stress-related high blood sugar levels may not benefit from this research.
What this research studies
This research investigates the impact of stress-induced high blood sugar levels on the treatment outcomes of tuberculosis (TB) and the subsequent risk of developing diabetes. It focuses on patients with TB, particularly in low- and middle-income countries like Georgia, where the dual burden of TB and diabetes poses significant health challenges. The study aims to understand how stress hyperglycemia influences TB treatment success and whether it contributes to diabetes risk after TB treatment. By analyzing biomarkers and treatment responses, the research seeks to improve management strategies for patients with TB who may also be at risk for diabetes.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment protocols for TB patients, potentially reducing the risk of developing diabetes.
How similar studies have gone: Previous research has indicated that managing stress hyperglycemia can improve treatment outcomes in other chronic diseases, suggesting potential for success in this area as well.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Magee, Matthew James — Emory University
- Study coordinator: Magee, Matthew James
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.