How stress, race, and thinking habits affect weight-loss success across income levels

Stress, race, and cognitive mediators of SES-related disparities in behavioral obesity treatment outcomes

NIH-funded research Rush University Medical Center · NIH-11171403

This project compares how stress, daily mental demands, and race relate to weight-loss program success for adults of lower versus higher socioeconomic status.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionRush University Medical Center NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11171403 on NIH RePORTER

What this research studies

You would join a standard behavioral weight-loss program where equal numbers of people from lower and higher income backgrounds are enrolled. Researchers will track your weight, activity (using devices like an accelerometer), daily stressors, and decision-making patterns called "present bias" to see how these factors influence sticking with the program. The team will also balance participants by race/ethnicity and follow everyone over time with regular check-ins and measurements. Findings will be used to design better weight-loss approaches that fit the real-life challenges people face.

Who could benefit from this research

Good fit: Adults aged 21 and older with overweight or obesity (including people with type 2 diabetes) who are willing to join a behavioral weight-loss program are ideal candidates.

Not a fit: Children, people unable to attend clinic visits in the Chicago area, or those with medical conditions that prevent participation in a standard weight-loss program are unlikely to benefit from joining this project.

Why it matters

Potential benefit: If successful, this work could lead to weight-loss programs that help people with lower income achieve better results by addressing stress and decision-making barriers.

How similar studies have performed: Previous weight-loss programs consistently show smaller results for lower-income groups, and work targeting decision-making and stress is promising but not yet proven to close that gap.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Adult-Onset Diabetes Mellitus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.