How stress in early life shapes infant brain activity and early learning

Longitudinal investigation of the relations among stress, brain activity, neurocognitive skill, and socioemotional functioning during infancy

NIH-funded research Columbia University Teachers College · NIH-11308840

This project follows infants and their caregivers to link chronic stress with babies' brain activity and early language, thinking, and social skills.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionColumbia University Teachers College NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11308840 on NIH RePORTER

What this research studies

You and your baby would be followed over time while researchers measure caregiver stress using multiple methods and record infants' resting brain activity. The team will also collect age‑appropriate tests of language, cognitive skills, and social/emotional behavior at several time points. By combining these different measures, researchers aim to trace how stress-related changes in brain activity relate to later school‑readiness skills. The work focuses on early infancy and how early brain differences may predict later learning and social outcomes.

Who could benefit from this research

Good fit: Ideal participants are infants (and their caregivers, often mothers) and families, especially those experiencing chronic stress, who can take part in repeated visits and measurements.

Not a fit: Older children, adults, or families not experiencing chronic stress are unlikely to receive direct benefit from this infant-focused observational research.

Why it matters

Potential benefit: If successful, this work could help identify early signs of risk and guide interventions to support learning and social development in children exposed to chronic stress.

How similar studies have performed: Previous studies have linked maternal stress to changes in infant resting brain activity, but it remains unclear whether those brain differences predict later language and socioemotional skills, so this approach is building on emerging but still limited evidence.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.