How stress hormones affect milk production in breastfeeding mothers

The role of glucocorticoids in the regulation of alpha-lactalbumin and milk production.

NIH-funded research University of California at Davis · NIH-11076290

This study looks at how stress hormones affect milk production in new moms, especially those who might be feeling extra stressed due to things like their baby being in the hospital or having a tough birth, and it hopes to find ways to help them produce more milk.

Quick facts

Grant typeFellowship grant
Study typeNIH-funded research
Funding institutionUniversity of California at Davis NIH-funded
Lab location1 site (Davis, United States)
Project IDNIH-11076290 on NIH RePORTER

What this research studies

This research investigates the impact of glucocorticoids, hormones released during stress, on the production of alpha-lactalbumin, a protein essential for milk synthesis. By using a mouse model, the study aims to understand how these hormones influence lactation, particularly in mothers who may experience stress due to factors like infant hospitalization or traumatic birth. The research will explore the mechanisms behind low milk supply and seek to identify potential treatments to support breastfeeding. The findings could lead to improved strategies for enhancing milk production in mothers facing challenges.

Who could benefit from this research

Good fit: Ideal candidates for this research are breastfeeding mothers, particularly those experiencing stress or difficulties with milk production.

Not a fit: Patients who are not breastfeeding or who do not have issues related to milk production may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could help increase breastfeeding rates and improve health outcomes for mothers and infants.

How similar studies have performed: Previous research has shown that understanding hormonal regulation can lead to significant improvements in breastfeeding outcomes, suggesting this approach has potential for success.

Where this research is happening

Davis, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.