How stress, cravings, and hormones affect returning to cannabis after childbirth

The Impact of Stress and Craving on Return to Postpartum Cannabis Use

NIH-funded research Medical University of South Carolina · NIH-11166356

This project will learn how stress, cravings, and changing hormone levels relate to women returning to cannabis use after having a baby.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMedical University of South Carolina NIH-funded
Lab location1 site (Charleston, United States)
Project IDNIH-11166356 on NIH RePORTER

What this research studies

You would be followed from late pregnancy into the months after birth with regular check-ins. Researchers will ask about stress, mood, sleep, and cravings and will measure hormone levels, including progesterone, over time. They will track if and when women resume cannabis use and link those patterns to stress and hormone changes. The information is intended to reveal patterns that could guide ways to prevent return to use after childbirth.

Who could benefit from this research

Good fit: Ideal candidates are pregnant or recently postpartum women who used cannabis before pregnancy and reduced or stopped use during pregnancy.

Not a fit: People who are not pregnant or postpartum, who have never used cannabis, or who need immediate treatment for heavy current cannabis dependence may not directly benefit from this research.

Why it matters

Potential benefit: If successful, this work could lead to targeted supports or treatments to help new mothers avoid returning to cannabis use and improve newborn and maternal health.

How similar studies have performed: Small prior studies suggest progesterone may reduce relapse to tobacco and cocaine, but it has not yet been tested specifically for postpartum cannabis return.

Where this research is happening

Charleston, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.