How stress at different levels affects young adults' smoking and vaping

Multilevel stress influences on longitudinal trajectories of tobacco use among young adults throughout the US

NIH-funded research University of Oklahoma Hlth Sciences Ctr · NIH-11362790

This project looks at how life stress, mental-health symptoms, and social pressures relate to smoking, vaping, and using multiple tobacco products among young adults across the U.S.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Oklahoma Hlth Sciences Ctr NIH-funded
Lab location1 site (Oklahoma City, United States)
Project IDNIH-11362790 on NIH RePORTER

What this research studies

This research follows young adults over time using periodic surveys and real-time phone prompts (ecological momentary assessment) to track smoking, vaping, and use of multiple tobacco products alongside stress and mental health. It examines personal, interpersonal, and neighborhood-level stressors to see how they relate to starting, increasing, or switching tobacco products, and whether tobacco use and stress influence each other. The team recruits participants from areas with different access to tobacco-cessation services to understand geographic differences. Results aim to identify specific moments and groups who might benefit from tailored support to prevent escalation or help quit.

Who could benefit from this research

Good fit: Ideal candidates are young adults (late teens through twenties) who currently use cigarettes, e-cigarettes, cigars, or multiple tobacco products, or who experience high stress or mental-health symptoms.

Not a fit: People who are outside the young adult age range or who never use tobacco products are unlikely to receive direct benefit from this project.

Why it matters

Potential benefit: If successful, the work could help pinpoint who is most at risk and when, so prevention and quitting support can be better timed and targeted for young adults.

How similar studies have performed: Previous research has linked stress and tobacco use but mostly for single products or one-way effects, so using longitudinal and real-time methods to capture bidirectional, polytobacco patterns is more novel.

Where this research is happening

Oklahoma City, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.