How stress and other factors influence heart health in different racial and ethnic groups
Racial/Ethnic Influences on Early Vascular Aging and Cardiac Strain: Role of Cumulative Stress, Inflammatory and Metabolic Burden
This project explores why heart and blood vessel problems start earlier in some racial and ethnic groups, looking at how stress, inflammation, and metabolism play a role.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California-Irvine NIH-funded |
| Lab location | 1 site (Irvine, United States) |
| Project ID | NIH-10884395 on NIH RePORTER |
What this research studies
Heart disease affects people from different racial and ethnic backgrounds unequally, often starting earlier in life for some groups. We believe that ongoing stress, along with inflammation and metabolic issues, might contribute to this early aging of blood vessels and heart strain. This project aims to understand these connections by looking at young people from diverse backgrounds. By measuring various heart health markers and stress indicators, we hope to uncover why these disparities exist and identify potential protective factors.
Who could benefit from this research
Good fit: This project is interested in adolescents and young adults from diverse racial and ethnic backgrounds who may be at risk for early heart and blood vessel changes.
Not a fit: Patients who are not adolescents or young adults, or those without risk factors for early cardiovascular changes, may not directly benefit from this specific project.
Why it matters
Potential benefit: If successful, this work could lead to new ways to prevent heart disease earlier in life, especially for those at higher risk due to their racial or ethnic background.
How similar studies have performed: While links between stress and heart health have been suggested, this project takes a novel approach by comprehensively studying these factors together in young, diverse populations.
Where this research is happening
Irvine, United States
- University of California-Irvine — Irvine, United States (Active)
Researchers
- Principal investigator: Rao, Uma — University of California-Irvine
- Study coordinator: Rao, Uma
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.