NIH-funded research NIH-funded research

How stress and negative emotions affect eating behavior in binge-eating disorder.

Official title: Understanding the Effects of Acute Stressors and Negative Emotion on Eating Behavior in Binge-Eating Disorder: The Role of Stressor-Induced Changes in Reward and Cognitive Control

Funded at Mclean Hospital · NIH-10456768 · Data updated 2026-11-12

This study is looking at how stress and negative feelings affect eating habits in young women with binge-eating disorder, hoping to find out why some people have a hard time controlling their eating even with treatment, which could help improve future care.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionMclean Hospital
NIH-funded
Lab location1 site (Belmont, United States)
Project startSeptember 1, 2018
Project endJuly 30, 2025
Funding year2022
Award (this year)$194,217
NIH project number5K23DK120517-05
Project IDNIH-10456768 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are young women aged 21 and older who have been diagnosed with binge-eating disorder.

Less likely to help

Patients who do not have binge-eating disorder or those under 21 years old may not benefit from this research.

What this research studies

This research investigates how acute stressors and negative emotions influence eating behaviors in individuals with binge-eating disorder (BED). It focuses on understanding the neurobiological mechanisms that link stress to increased food cravings and binge eating episodes. By examining brain activity and food choices in response to stress, the study aims to uncover why some individuals with BED struggle to manage their eating despite treatment. Participants will be young women diagnosed with BED, and the findings could lead to improved treatment strategies.

Why it matters

Potential benefit: If successful, this research could lead to more effective interventions for individuals with binge-eating disorder by addressing the underlying emotional and stress-related triggers of their eating behaviors.

How similar studies have gone: Previous research has shown promising results in understanding the relationship between stress and eating behaviors, suggesting that this approach could yield valuable insights.

Where this research is happening

  • Mclean Hospital
    Belmont, United States
    Active

Researchers

  • Principal investigator: Javaras, Kristin N. — Mclean Hospital
  • Study coordinator: Javaras, Kristin N.

Related research

Other NIH-funded projects on the same topics.

  • Understanding Binge Eating Disorder in Older Hispanic Women

    This project looks at how chronic binge eating disorder affects the health of older Hispanic women who also face challenges with food security.

    NIH research University of Texas Hlth Science Center · San Antonio, United States · NIH-11190801

  • Social media habits and binge-eating in teens

    This project will see if patterns of social media use predict binge-eating behaviors in adolescents.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-11122359

  • Using digital mindfulness meditation to improve therapy for binge eating disorder

    This study is testing a new online program that combines mindfulness meditation with traditional therapy to help people with binge eating disorder feel better and manage their eating habits more effectively.

    NIH research Yeshiva University · New York, United States · NIH-11077250

  • Exploring how social media use affects binge-eating disorder in adolescents

    This study looks at how using social media a lot might be linked to binge-eating in teens, especially considering things like feeling sad, anxious, or being bullied online, and it hopes to offer helpful advice for teens, their parents, and doctors to prevent these eating issues.

    NIH research University of California, San Francisco · San Francisco, United States · NIH-10928216

  • Impact of binge eating disorder on older Hispanic women facing food insecurity

    This study is looking at how binge eating disorder affects Hispanic women over 65 who don’t always have enough food, to better understand their health challenges and improve care for them.

    NIH research University of Texas Hlth Science Center · San Antonio, United States · NIH-10872852

  • Investigating brain changes in binge eating disorder using advanced imaging techniques

    This study is looking at how binge eating disorder affects the brain by using a special imaging technique to see changes in brain connections, and it's for people who want to help improve treatments for this condition.

    NIH research Yale University · New Haven, United States · NIH-10836030

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.