How stress and genetics affect asthma in children
Psychosocial and Genetic Effects on Gene Expression and Asthma
This study is looking at how stress and genetics can affect asthma symptoms in kids, and it’s for children with asthma and their healthy siblings to help find better ways to manage their condition.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Wayne State University NIH-funded |
| Lab location | 1 site (Detroit, United States) |
| Project ID | NIH-11003969 on NIH RePORTER |
What this research studies
This research investigates how psychosocial stressors and genetic factors influence asthma symptoms in children. By analyzing blood samples from children with asthma and their healthy siblings, the study aims to understand how these factors affect gene expression related to immune function. The researchers will use advanced techniques like RNA sequencing to identify specific genetic variations and psychosocial influences that contribute to asthma severity. This comprehensive approach seeks to uncover personalized strategies for managing asthma in affected children.
Who could benefit from this research
Good fit: Ideal candidates for this research are children aged 0-11 years with asthma, particularly those from African ancestry.
Not a fit: Patients who do not have asthma or are outside the age range of 0-11 years may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to personalized treatments that improve asthma management and overall health for children.
How similar studies have performed: Previous research has shown promising results in understanding the relationship between psychosocial factors and asthma, making this approach both relevant and potentially impactful.
Where this research is happening
Detroit, United States
- Wayne State University — Detroit, United States (Active)
Researchers
- Principal investigator: Pique-Regi, Roger — Wayne State University
- Study coordinator: Pique-Regi, Roger
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.