How stress affects obesity-related pancreatic cancer
Official title: Stress adaptation in obesity-associated pancreatic cancer
Funded at Thomas Jefferson University · NIH-10907433 · Data updated 2026-11-12
This study is looking at how stress affects pancreatic cancer in people who are obese, hoping to find ways to improve treatments and help patients feel better by understanding their body's responses to stress.
Quick facts
| Grant type | R37 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Thomas Jefferson University NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | July 1, 2023 |
| Project end | June 30, 2025 |
| Funding year | 2024 |
| Award (this year) | $339,007 |
| NIH project number | 5R37CA230645-07 |
| Project ID | NIH-10907433 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with pancreatic cancer who also have obesity and experience significant stress.
✕Less likely to help
Patients without obesity or those who do not have pancreatic cancer may not benefit from this research.
What this research studies
This research investigates the relationship between stress and pancreatic cancer in individuals with obesity. It aims to understand how stress adaptation mechanisms may influence the progression of cancer and the effectiveness of treatments. By examining biological responses and signaling pathways, the study seeks to identify potential therapeutic targets that could improve patient outcomes. Patients may be involved in providing biological samples or participating in assessments related to stress and health.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for managing pancreatic cancer in obese patients, potentially improving survival rates and quality of life.
How similar studies have gone: While the specific focus on stress adaptation in obesity-related pancreatic cancer is novel, there have been successful studies exploring the impact of stress on cancer progression in other contexts.
Where this research is happening
-
Thomas Jefferson University
Philadelphia, United States Active
Researchers
- Principal investigator: Grabocka, Elda — Thomas Jefferson University
- Study coordinator: Grabocka, Elda
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.