How stress affects eating habits and obesity

Stress, 'comfort' food, and obesity

NIH-funded research University of Cincinnati · NIH-10604369

This study looks at how people turn to high-calorie comfort foods when they're stressed and how this can lead to weight gain, especially by comparing how normal-weight and obese individuals respond to stress and food, using a controlled experiment with rats to better understand this connection.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Cincinnati NIH-funded
Lab location1 site (Cincinnati, United States)
Project IDNIH-10604369 on NIH RePORTER

What this research studies

This research investigates how people use 'comfort' foods, which are often high in calories, to cope with stress and how this behavior can lead to obesity. It aims to understand the biological mechanisms that allow these foods to provide stress relief in individuals with normal weight and how this process is disrupted in those who are obese. By using a controlled feeding experiment with rats, the study will explore the relationship between stress, food intake, and body weight, providing insights into the cycle of stress and overeating.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults over 21 who struggle with stress-related eating and obesity.

Not a fit: Patients who do not experience stress-related eating or who are not affected by obesity may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better strategies for managing stress-related eating and obesity, improving overall metabolic health.

How similar studies have performed: Previous research has shown that understanding the relationship between stress and eating behaviors can lead to effective interventions, suggesting that this approach has potential for success.

Where this research is happening

Cincinnati, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.