How stress affects bladder pain and function
Contribution of Stress Induced Autonomic and Urothelial Dysregulation to IC/BPS
['FUNDING_R01'] · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · NIH-10425403
This study is looking at how emotional stress might affect people with interstitial cystitis/bladder pain syndrome (IC/BPS) by exploring how stress can change bladder function and worsen symptoms, with the goal of finding better ways to manage this condition.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF PITTSBURGH AT PITTSBURGH (nih funded) |
| Locations | 1 site (PITTSBURGH, UNITED STATES) |
| Trial ID | NIH-10425403 on ClinicalTrials.gov |
What this research studies
This research investigates the relationship between emotional stress and interstitial cystitis/bladder pain syndrome (IC/BPS), a chronic condition characterized by bladder pain and frequent urination. The study aims to understand how stress may lead to changes in the autonomic nervous system and bladder function, potentially worsening symptoms. Researchers will employ various methods, including molecular biology techniques and imaging, to explore the biological mechanisms behind stress-induced bladder dysfunction. By examining these connections, the research seeks to uncover new insights into the management of IC/BPS.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with interstitial cystitis/bladder pain syndrome who experience significant stress.
Not a fit: Patients with bladder pain not related to stress or those without a diagnosis of IC/BPS may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment options for patients suffering from IC/BPS by addressing the role of stress in their symptoms.
How similar studies have performed: Previous research has indicated a connection between stress and chronic pain conditions, suggesting that this approach may yield valuable insights.
Where this research is happening
PITTSBURGH, UNITED STATES
- UNIVERSITY OF PITTSBURGH AT PITTSBURGH — PITTSBURGH, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: BIRDER, LORI A — UNIVERSITY OF PITTSBURGH AT PITTSBURGH
- Study coordinator: BIRDER, LORI A
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.