How state COVID rules affected adults' mental health, overdoses, and suicide

States' COVID-19 Mitigation Policies and Psychological Health, Drug Overdose, and Suicide among U.S. Adults

NIH-funded research Syracuse University · NIH-11177947

This project looks at how state COVID-19 policies like lockdowns and financial supports changed mental health, overdose deaths, and suicide risk for U.S. adults.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionSyracuse University NIH-funded
Lab location1 site (Syracuse, United States)
Project IDNIH-11177947 on NIH RePORTER

What this research studies

From a participant's view, researchers combine adults' self-reports about how COVID and related policies affected their lives with county-level records of overdose and suicide deaths to see patterns over time. They create composite measures of state policies (for example, stay-at-home orders, eviction bans, and unemployment benefits) and use advanced statistical models to link those policies to changes in mental health and mortality. The team compares short- and longer-term effects and adjusts for differences across counties, ages, and time periods to isolate policy impacts.

Who could benefit from this research

Good fit: Adults (21 and older) living in the United States, especially working-age and older adults who experienced pandemic-related policies and are willing to report how those policies affected their mental health, are the ideal candidates for participation.

Not a fit: People under 21, non-U.S. residents, or individuals seeking immediate clinical treatment for mental health or substance use conditions are unlikely to directly benefit from this research.

Why it matters

Potential benefit: If successful, the findings could guide future state policies to better protect mental health and reduce overdose and suicide during public health emergencies.

How similar studies have performed: Previous studies have linked pandemic policies to mental health and overdose trends with mixed results, and this project uses new combined data and modeling to provide clearer insights.

Where this research is happening

Syracuse, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.