NIH-funded research R21 grant

How speech listening and learning affect speaking in Parkinson's

Official title: Relationship between speech perceptual learning and speech production in Parkinson’s disease

Funded at State University of New York at Buffalo · NIH-11254926 · Data updated 2026-11-12

This project looks at whether people with Parkinson's who have trouble learning speech sounds also have related difficulties changing how they speak.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionState University of New York at Buffalo
NIH-funded
Lab location1 site (Amherst, United States)
Project startJanuary 6, 2025
Project endDecember 31, 2027
Funding year2026
Award (this year)$201,250
NIH project number5R21DC022390-02
Project IDNIH-11254926 on NIH RePORTER

Who could benefit from this research

Could help

Adults with Parkinson's disease who notice changes in their speech (for example softer, slower, or less clear speech) and who can complete listening and speaking tasks are ideal candidates.

Less likely to help

People without speech problems, those with severe cognitive impairment who cannot follow tasks, or those unable to travel to the study site are unlikely to benefit directly from participation.

What this research studies

You would take part in listening tasks and short training sessions while researchers record your speech. They will measure acoustic features like rate, loudness, and clarity and compare how well people learn new speech patterns. The team will look for links between how you perceive and learn speech and how you produce it. Findings will be used to guide better, more personalized speech therapy approaches.

Why it matters

Potential benefit: If successful, this research could help speech therapists tailor treatments to each person's ability to perceive and learn speech, improving everyday communication.

How similar studies have gone: Some established speech therapies help people with Parkinson's, but directly linking speech perceptual learning to speech production is a newer, less-tested approach.

Where this research is happening

  • State University of New York at Buffalo
    Amherst, United States
    Active

Researchers

  • Principal investigator: Dinino, Mishaela T — State University of New York at Buffalo
  • Study coordinator: Dinino, Mishaela T

Related research

Other NIH-funded projects on the same topics.

  • Tracking breathing, voice, and speech changes in Parkinson's disease

    This project follows people with Parkinson's and links changes in breathing, voice, and mouth movements to everyday speech and communication problems.

    NIH research Boston University (Charles River Campus) · Boston, United States · NIH-11264783

  • How speech perception affects speech production in Parkinson's disease

    This study is looking at how people with Parkinson's disease hear and produce speech to find out why some have a harder time speaking after therapy, with the goal of creating better, personalized help for them.

    NIH research State University of New York at Buffalo · Amherst, United States · NIH-11043529

  • Understanding how speech changes in Parkinson's disease

    This study looks at how the way you speak changes with Parkinson's disease and how that affects your communication experience, so we can find out what really matters to you and help doctors choose the best treatments.

    NIH research Boston University (Charles River Campus) · Boston, United States · NIH-11010337

  • Gut-brain clues in Parkinson’s disease: supplement to a large registry

    A plant-wide supplement to an NIH program will enroll people with Parkinson’s, with and without GI symptoms, plus healthy controls, to study how gut function, brain signals, and sleep rhythms relate to Parkinson’s symptoms.

    NIH research Columbia University Health Sciences · New York, United States · NIH-11612995

  • Gut-brain connections in Parkinson’s disease: how the gut and environment shape symptoms

    A Mayo Clinic team is studying how gut problems, environmental factors, and genetics together influence Parkinson’s disease and its GI symptoms to find biomarkers and better understanding of the disease.

    NIH research Mayo Clinic Rochester · Rochester, United States · NIH-11596497

  • Gut-brain communication in Parkinson’s disease for better symptoms and daily life

    This project enrolls people with Parkinson’s disease and healthy controls to build a big registry and study how gut function, brain signals, sleep, and circadian rhythms relate to PD symptoms.

    NIH research Columbia University Health Sciences · New York, United States · NIH-11593798

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.