How specific proteins influence cancer development
Regulation of Human Tumorigensis by Cancer Specific NXF1 Adaptor Proteins
This study is looking at how certain proteins help control the movement of messages in skin cells that can lead to cancer, with the hope of finding new ways to treat skin tumors.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Diego NIH-funded |
| Lab location | 1 site (La Jolla, United States) |
| Project ID | NIH-11076228 on NIH RePORTER |
What this research studies
This research investigates how certain adaptor proteins regulate the export of specific mRNAs that contribute to cancer progression. By focusing on a model of skin tumors, the study aims to understand the molecular mechanisms that lead to the transition from normal skin cells to cancerous ones. The researchers will identify which adaptor proteins are involved and how they affect the expression of oncogenic genes. This could provide insights into potential therapeutic targets for cancer treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research would include individuals with skin tumors or those at high risk for developing skin cancer.
Not a fit: Patients with cancers unrelated to skin or those who do not have any genetic predisposition to skin tumors may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new strategies for preventing or treating certain types of cancer by targeting the molecular mechanisms involved in tumorigenesis.
How similar studies have performed: Other research has shown success in targeting molecular mechanisms in cancer, suggesting that this approach could yield valuable insights.
Where this research is happening
La Jolla, United States
- University of California, San Diego — La Jolla, United States (Active)
Researchers
- Principal investigator: Sen, George L — University of California, San Diego
- Study coordinator: Sen, George L
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.