How socioeconomic factors affect brain health and cognitive decline in adults

Socioeconomic Mediators of Adult Brain Network Resilience and Vulnerability to Cognitive Decline

NIH-funded research University of Texas Dallas · NIH-10622506

This study is looking at how money and social status affect brain health and thinking skills in people aged 40 to 59, especially those from lower to middle-class backgrounds, to find out what helps them stay sharp even when they face challenges.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Texas Dallas NIH-funded
Lab location1 site (Richardson, United States)
Project IDNIH-10622506 on NIH RePORTER

What this research studies

This research investigates how socioeconomic status influences cognitive decline and brain health in middle-aged adults. It focuses on individuals aged 40-59 from lower to middle-class backgrounds, measuring their brain function and cognitive abilities over time. Using non-invasive brain imaging techniques, the study aims to identify factors that contribute to resilience against cognitive decline, even in those at higher risk due to socioeconomic disadvantages. Participants will undergo assessments to track changes in their cognitive abilities and brain network organization over a period of 3.5 years.

Who could benefit from this research

Good fit: Ideal candidates for this research are middle-aged adults aged 40-59 from lower to middle socioeconomic backgrounds.

Not a fit: Patients outside the age range of 40-59 or those from higher socioeconomic backgrounds may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and interventions for preventing cognitive decline in at-risk populations.

How similar studies have performed: Previous research has shown that socioeconomic factors significantly impact cognitive health, suggesting that this approach could yield valuable insights.

Where this research is happening

Richardson, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Alzheimer disease dementiaAlzheimer syndrome
Last reviewed 2026-06-10 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.