How social stressors affect chronic disease in women

The Impact of Environmental Stressors on Chronic Disease Disparities in Women

NIH-funded research University of Nebraska Medical Center · NIH-11089587

This study is looking at how tough life experiences and money worries can speed up aging and affect health in women, especially those who have faced trauma, to better understand how these challenges relate to conditions like PTSD, diabetes, and high blood pressure.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Nebraska Medical Center NIH-funded
Lab location1 site (Omaha, United States)
Project IDNIH-11089587 on NIH RePORTER

What this research studies

This research investigates how social stressors, such as trauma and socioeconomic factors, influence the acceleration of biological aging and chronic health disparities in women. By analyzing a cohort of women who have experienced significant trauma, the study aims to understand the relationship between traumatic stress and health outcomes, including psychological conditions like PTSD and physical diseases such as diabetes and hypertension. The research will also explore how factors like social support and financial strain may impact these health outcomes over time. Blood samples will be collected to assess biological age through DNA methylation, providing insights into the underlying mechanisms of health disparities.

Who could benefit from this research

Good fit: Ideal candidates for this research are women who have experienced significant trauma and are facing chronic health issues.

Not a fit: Patients who do not have a history of trauma or chronic health conditions may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved understanding and interventions for chronic diseases in women affected by social stressors.

How similar studies have performed: Previous research has shown that social stressors can significantly impact health outcomes, suggesting that this approach may yield valuable insights.

Where this research is happening

Omaha, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions age associated disease
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.