NIH-funded research NIH-funded research

How social stress affects alcohol drinking behavior

Official title: Corticolimbic Neuroimmune Determinants of Social Stress-Associated Alcohol Drinking

Funded at Northwestern University at Chicago · NIH-11087906 · Data updated 2026-11-12

This study looks at how feeling stressed in social situations might lead some people, especially those who feel less socially connected, to drink more alcohol to feel better, and it hopes to find out how this happens in the brain so we can help those at risk for drinking problems.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago
NIH-funded
Lab location1 site (Chicago, United States)
Project startApril 5, 2022
Project endAugust 31, 2026
Funding year2024
Award (this year)$62,378
NIH project number3R00AA029180-04S1
Project IDNIH-11087906 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who experience social stress and may use alcohol as a coping mechanism.

Less likely to help

Patients who do not experience social stress or do not consume alcohol may not benefit from this research.

What this research studies

This research investigates the connection between social stress and alcohol consumption, focusing on how individuals with lower social rank may be more likely to drink alcohol to cope with negative emotions. By studying the brain's amygdala-cortical circuit and immune responses, the research aims to uncover the biological mechanisms that drive increased alcohol use in response to social isolation. The findings could help identify individuals at risk for developing alcohol use disorders and inform potential interventions.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment options for individuals struggling with alcohol use disorders related to social stress.

How similar studies have gone: Previous research has shown that social stress can influence alcohol consumption patterns, suggesting that this approach has a foundation in established findings.

Where this research is happening

  • Northwestern University at Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Patel, Reesha — Northwestern University at Chicago
  • Study coordinator: Patel, Reesha

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.