How social stress affects alcohol drinking behavior

Corticolimbic Neuroimmune Determinants of Social Stress-Associated Alcohol Drinking

NIH-funded research Northwestern University at Chicago · NIH-11087906

This study looks at how feeling stressed in social situations might lead some people, especially those who feel less socially connected, to drink more alcohol to feel better, and it hopes to find out how this happens in the brain so we can help those at risk for drinking problems.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNorthwestern University at Chicago NIH-funded
Lab location1 site (Chicago, United States)
Project IDNIH-11087906 on NIH RePORTER

What this research studies

This research investigates the connection between social stress and alcohol consumption, focusing on how individuals with lower social rank may be more likely to drink alcohol to cope with negative emotions. By studying the brain's amygdala-cortical circuit and immune responses, the research aims to uncover the biological mechanisms that drive increased alcohol use in response to social isolation. The findings could help identify individuals at risk for developing alcohol use disorders and inform potential interventions.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who experience social stress and may use alcohol as a coping mechanism.

Not a fit: Patients who do not experience social stress or do not consume alcohol may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to better understanding and treatment options for individuals struggling with alcohol use disorders related to social stress.

How similar studies have performed: Previous research has shown that social stress can influence alcohol consumption patterns, suggesting that this approach has a foundation in established findings.

Where this research is happening

Chicago, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.