How social relationships affect gene regulation in baboons over their lifetime

Gene regulation and social relationships across the life course in a nonhuman primate model

NIH-funded research Duke University · NIH-11093478

This study is looking at how friendships and social connections in baboons can affect their health and genes, helping us understand why some animals—and maybe even people—are more affected by feeling lonely.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionDuke University NIH-funded
Lab location1 site (Durham, United States)
Project IDNIH-11093478 on NIH RePORTER

What this research studies

This research investigates the connection between social relationships and gene regulation using baboons as a model. By studying a population of baboons in Kenya, researchers will analyze how social ties influence health outcomes and gene expression from birth through adulthood. The study aims to uncover why some individuals are more vulnerable to the effects of social isolation, linking social experiences to biological markers. This approach combines longitudinal social data with molecular analysis to provide insights into health disparities related to social integration.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals interested in the effects of social relationships on health, particularly those who may experience social isolation.

Not a fit: Patients who are not affected by social isolation or who do not have an interest in the biological underpinnings of social relationships may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a better understanding of how social relationships impact health, potentially informing interventions to improve well-being in humans.

How similar studies have performed: Previous research has shown promising results in understanding the health impacts of social relationships, making this approach both relevant and potentially impactful.

Where this research is happening

Durham, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
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Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.