How social isolation affects aging and health in people with schizophrenia

The impact of social isolation on aging health in schizophrenia

['FUNDING_R01'] · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · NIH-11161436

This project looks at whether being socially isolated makes people with schizophrenia develop age-related health problems earlier.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorICAHN SCHOOL OF MEDICINE AT MOUNT SINAI (nih funded)
Locations1 site (NEW YORK, UNITED STATES)
Trial IDNIH-11161436 on ClinicalTrials.gov

What this research studies

You would join an international group of about 650 people who will be followed over time to track health as they age. The study brings together participants from Europe (EU-GEI) and the US (Olin Neuropsychiatry Research Center) and includes roughly 500 people with schizophrenia plus others for comparison. Researchers will gather information on social contacts, health history, medical conditions, lifestyle, and regular follow-ups to see how social isolation relates to physical health over the years. The goal is to learn whether loneliness or lack of social connection contributes to earlier onset of age-related illnesses in people with schizophrenia.

Who could benefit from this research

Good fit: Adults diagnosed with schizophrenia—especially older adults or those who have limited social contact—would be the main candidates for this work.

Not a fit: People without schizophrenia or those who are younger and not socially isolated may not directly benefit from this specific study.

Why it matters

Potential benefit: If successful, this could point to improving social support as a way to slow premature aging and boost long-term health for people with schizophrenia.

How similar studies have performed: Prior pilot studies and research in the general population link social isolation to worse health, but longitudinal studies focused on schizophrenia remain limited.

Where this research is happening

NEW YORK, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.