How social interactions influence motivation and behavior in the brain

Brain mechanisms underlying how social stimuli elicit motivated behavior

NIH-funded research Columbia University Health Sciences · NIH-11056943

This study looks at how our brains respond to social situations, like interacting with friends, by exploring how social status affects our feelings and motivations, using mice to help us understand the science behind social behavior and emotions.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionColumbia University Health Sciences NIH-funded
Lab location1 site (New York, United States)
Project IDNIH-11056943 on NIH RePORTER

What this research studies

This research investigates the brain mechanisms that drive motivated behavior in response to social stimuli, such as interactions with peers. It focuses on understanding how social hierarchies affect emotional responses and motivation by examining specific brain regions, particularly the anterior cingulate cortex and the basolateral amygdala. By studying groups of mice with established social ranks, the research aims to uncover how social information is processed and integrated into the neural circuits that govern behavior. This could provide insights into the biological underpinnings of social behavior and emotional responses.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would include individuals experiencing social anxiety, aggression, or other behavioral issues related to social interactions.

Not a fit: Patients who do not have social interaction challenges or behavioral issues may not receive direct benefits from this research.

Why it matters

Potential benefit: If successful, this research could lead to a better understanding of how social dynamics influence behavior, potentially informing treatments for social and emotional disorders.

How similar studies have performed: Previous research has shown success in understanding neural mechanisms of behavior through similar approaches, although this specific focus on social stimuli is relatively novel.

Where this research is happening

New York, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.