How social factors affect gene expression and health in HIV-positive men who have sex with men using methamphetamine
Trajectories of socially regulated gene expression, methamphetamine use, and viral load among HIV-positive men who have sex with men (MSM) receiving contingency management
This study is looking at how social factors and stress might affect the health of HIV-positive men who have sex with men and use methamphetamine, to help find better ways to treat and prevent issues related to both addiction and HIV.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California Los Angeles NIH-funded |
| Lab location | 1 site (Los Angeles, United States) |
| Project ID | NIH-11051153 on NIH RePORTER |
What this research studies
This research investigates the relationship between social influences, gene expression, and health outcomes in HIV-positive men who have sex with men (MSM) who are also using methamphetamine. The study aims to understand how stress-related gene markers may link to addiction and the progression of HIV disease. By employing advanced analytical methods and clinical trial techniques, the research seeks to provide insights that could improve treatment and prevention strategies for this population. Participants will be monitored for their viral load and substance use, contributing to a better understanding of the interplay between addiction and HIV.
Who could benefit from this research
Good fit: Ideal candidates for this research are HIV-positive men who have sex with men and are currently using methamphetamine.
Not a fit: Patients who are not HIV-positive or who do not use methamphetamine may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved treatment strategies for HIV-positive MSM struggling with methamphetamine addiction.
How similar studies have performed: Previous research has shown promising results in understanding the links between social factors and health outcomes in similar populations, indicating that this approach has potential for success.
Where this research is happening
Los Angeles, United States
- University of California Los Angeles — Los Angeles, United States (Active)
Researchers
- Principal investigator: Li, Michael Jonathan — University of California Los Angeles
- Study coordinator: Li, Michael Jonathan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.