How Social Experiences Shape Behavior Through Gene Changes

Epigenetic control of behavior

NIH-funded research Ut Southwestern Medical Center · NIH-11124839

This research explores how social experiences can change gene activity and influence behavior, using ants as a model to understand these processes.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUt Southwestern Medical Center NIH-funded
Lab location1 site (Dallas, United States)
Project IDNIH-11124839 on NIH RePORTER

What this research studies

This project looks at how social interactions, like winning or losing in a group, can lead to lasting changes in behavior by affecting how genes work. We are using a special type of ant, Harpegnathos saltator, because they can change their social role and behavior as adults, which is linked to changes in their genes and brain. By studying these ants, we hope to learn more about how social life can physically alter the brain and behavior. This could help us understand similar processes in humans related to conditions like autism and behavior disorders.

Who could benefit from this research

Good fit: This foundational research does not directly involve human participants, but its findings may eventually be relevant to adults experiencing autistic disorder or other behavior disorders.

Not a fit: Patients seeking immediate treatment or direct participation in a clinical trial will not find direct benefit from this basic science project.

Why it matters

Potential benefit: If successful, this basic science could provide fundamental insights into how social experiences influence brain function and behavior, potentially informing future approaches for human behavioral disorders.

How similar studies have performed: While the use of Harpegnathos saltator ants as a model for epigenetic control of social behavior is novel, the broader field of epigenetics and behavior is an active area of research.

Where this research is happening

Dallas, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Autistic DisorderBehavior Disorders
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.