How social connections affect mental health, substance use, and HIV care during COVID

Social connections, risk for COVID-era psychiatric and substance use disorders, and HIV control

NIH-funded research Suny Downstate Medical Center · NIH-11230247

This project looks at how loneliness and social connections relate to mental health, substance use, and staying on HIV treatment for people living with HIV during the COVID era.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSuny Downstate Medical Center NIH-funded
Lab location1 site (Brooklyn, United States)
Project IDNIH-11230247 on NIH RePORTER

What this research studies

If you live with HIV, researchers will follow people over time to see how social connection, loneliness, and pandemic-related losses affect depression, substance use, and HIV care. They will collect surveys, interviews, and medical data such as medication adherence and viral load to link social experiences with health outcomes. The team uses mixed methods and works with community partners to capture diverse experiences, with attention to groups disproportionately affected such as African American communities. Findings aim to show which social supports or interventions could help people manage HIV and mental health better.

Who could benefit from this research

Good fit: Ideal candidates are adults living with HIV who have experienced social isolation, loneliness, or changes in social support during the COVID pandemic.

Not a fit: People who do not have HIV or who are not affected by social isolation or substance use are unlikely to benefit directly from this research.

Why it matters

Potential benefit: If successful, this work could point to ways to reduce loneliness and improve mental health, substance use outcomes, and HIV treatment adherence for people living with HIV.

How similar studies have performed: Prior research has linked loneliness to worse mental health and poorer HIV adherence, but few large national longitudinal studies combining interviews and medical data during COVID have been done.

Where this research is happening

Brooklyn, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.