How social circumstances and genetics influence health as we age in three countries

Social Circumstances and Epigenomics Promoting Health in Three Countries

['FUNDING_R01'] · UNIVERSITY OF SOUTHERN CALIFORNIA · NIH-11090391

This study looks at how your life experiences, both as a child and an adult, can change your genes and affect your health as you get older, especially for people over 50, to help create better health strategies just for you.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF SOUTHERN CALIFORNIA (nih funded)
Locations1 site (Los Angeles, UNITED STATES)
Trial IDNIH-11090391 on ClinicalTrials.gov

What this research studies

This research investigates the relationship between social circumstances and epigenetic changes that affect health in individuals over 50 years old. By analyzing existing data from three major studies in the US, Northern Ireland, and Ireland, the project aims to understand how childhood and adult life experiences impact genetic markers associated with aging. The research will also explore how these epigenetic changes correlate with health outcomes, providing insights into the complex interplay between environment and biology. Patients may benefit from findings that could inform personalized health strategies based on their life experiences.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals aged 50 and older who have experienced varying social and economic circumstances throughout their lives.

Not a fit: Patients under the age of 50 or those without significant social or economic variability in their life experiences may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved health strategies that consider both social and genetic factors in aging populations.

How similar studies have performed: Previous research has shown promising results in understanding the links between social factors and health outcomes, suggesting that this approach could yield valuable insights.

Where this research is happening

Los Angeles, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.