How social and economic stigma affects HIV and mental health in men

Characterizing the role of social, behavioral, and economic stigmas as determinants of HIV and mental health across the US

NIH-funded research Johns Hopkins University · NIH-11400278

This project looks at how different kinds of stigma influence HIV risk and mental health among men at higher risk in the United States.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionJohns Hopkins University NIH-funded
Lab location1 site (Baltimore, United States)
Project IDNIH-11400278 on NIH RePORTER

What this research studies

You'll be asked to complete online surveys about experiences of stigma, mental health, sexual behavior, and social and economic factors through the American Men’s Internet Survey. Each year researchers will enroll about 5,000 high-risk men in cross-sectional surveys and invite a subset (about 500 per survey) to provide self-collected biospecimens by mail. The team will measure enacted, perceived, and anticipated stigmas tied to things like income, occupation, demographics, and health behaviors and link those measures to HIV, STI, and mental health indicators. Findings will be used to pinpoint the pathways where stigma creates barriers so future programs can reduce risk and improve care.

Who could benefit from this research

Good fit: Men in the U.S. who are at higher risk for HIV—willing to complete online surveys and, if selected, to collect and mail biospecimens—are ideal candidates.

Not a fit: People who are not men, not living in the United States, or not at increased risk for HIV are unlikely to see direct benefit from participating.

Why it matters

Potential benefit: If successful, this work could reveal clear targets for reducing stigma and improving HIV prevention and mental health services for men at high risk.

How similar studies have performed: Prior research has linked stigma to worse HIV and mental health outcomes, but measurement and causal pathways remain limited, so this work builds on existing evidence with larger repeated surveys and biospecimen testing.

Where this research is happening

Baltimore, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Acquired Immune Deficiency Syndrome VirusAcquired Immunodeficiency Syndrome Virus
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.