How social and body clock changes affect depression during menopause

Investigation of Social and Circadian Rhythm Dysregulation in the Development of Depression Symptoms During the Menopause Transition

['FUNDING_R21'] · UNIVERSITY OF PENNSYLVANIA · NIH-10665761

This study is looking at how social interactions and daily rhythms affect mood in women going through menopause, whether or not they have depression, to help find better ways to support their mental health during this time.

Quick facts

Phase['FUNDING_R21']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF PENNSYLVANIA (nih funded)
Locations1 site (PHILADELPHIA, UNITED STATES)
Trial IDNIH-10665761 on ClinicalTrials.gov

What this research studies

This research investigates how changes in social interactions and circadian rhythms contribute to depression symptoms in women going through menopause. It aims to understand the relationship between hormonal fluctuations and environmental factors that may influence mood during this transition. The study will involve women both with and without significant depression symptoms, using interviews and self-report measures to gather data on their experiences and daily routines. By exploring these connections, the research seeks to inform better prevention and management strategies for depression during menopause.

Who could benefit from this research

Good fit: Ideal candidates for this research are women in the perimenopausal stage, particularly those experiencing symptoms of depression.

Not a fit: Patients who are not in the menopausal transition or who do not experience depressive symptoms may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to improved strategies for preventing and managing depression in women undergoing menopause.

How similar studies have performed: Previous research has indicated a link between circadian rhythm disruptions and depression, suggesting that this approach may yield valuable insights.

Where this research is happening

PHILADELPHIA, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.