How social and biological factors shape health in young cancer survivors
Social genomic mechanisms of health disparities among Adolescent and Young Adult (AYA) cancer survivors
This project looks at how life experiences and social conditions change gene activity and health in adolescent and young adult cancer survivors.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project ID | NIH-11191385 on NIH RePORTER |
What this research studies
If you join, you'll be one of 350 adolescent and young adult cancer survivors followed for five years after treatment to learn how social experiences affect health. You'll complete repeated questionnaires about stress, support, and life circumstances and give blood samples for tests of gene activity. The study focuses on people treated within the past three years for Hodgkin or non-Hodgkin lymphoma or acute lymphocytic leukemia. The team will link your social and biological data to long-term health outcomes like late effects and quality of life.
Who could benefit from this research
Good fit: Ideal candidates are adolescents and young adults who finished treatment within the past three years for Hodgkin or non-Hodgkin lymphoma or acute lymphocytic leukemia.
Not a fit: People who are not survivors of these specific cancers, who finished treatment more than three years ago, or who cannot provide blood samples may not directly benefit from participation.
Why it matters
Potential benefit: If successful, this work could clarify why some young survivors have poorer health and point to social or biological targets for reducing those differences.
How similar studies have performed: Related social-genomic studies have linked stress and social factors to changes in gene regulation in other groups, but applying this approach to AYA cancer survivors is relatively new.
Where this research is happening
Ann Arbor, United States
- University of Michigan at Ann Arbor — Ann Arbor, United States (Active)
Researchers
- Principal investigator: Zebrack, Bradley Jay — University of Michigan at Ann Arbor
- Study coordinator: Zebrack, Bradley Jay
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.