NIH-funded research R01 grant

How sleep patterns and gut bacteria in infants affect rapid weight gain

Official title: Investigating the Influences of Sleep‐Wake Patterns and Gut Microbiome Development in Infancy on Rapid Weight Gain, an Early Risk Factor for Obesity

Funded at Arizona State University-Tempe Campus · NIH-10770407 · Data updated 2026-11-12

This study is looking at how babies' sleep habits and gut bacteria affect their weight gain in the first six months, with the goal of finding ways to help prevent obesity and keep kids healthy as they grow.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionArizona State University-Tempe Campus
NIH-funded
Lab location1 site (Tempe, United States)
Project startFebruary 1, 2020
Project endJanuary 31, 2026
Funding year2024
Award (this year)$578,899
NIH project number5R01HL147931-05
Project IDNIH-10770407 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation include infants under six months old, particularly those with varying sleep patterns and feeding methods.

Less likely to help

Patients who are older than six months or those without concerns related to weight gain or sleep issues may not benefit from this research.

What this research studies

This research investigates how sleep-wake patterns and the development of gut microbiome in infants influence rapid weight gain during the first six months of life. It aims to understand the relationship between sleep quality, gut bacteria, and the risk of obesity, which can lead to serious health issues later in life. By examining these factors, the study seeks to identify early interventions that could help prevent obesity in children. The research will involve monitoring sleep patterns and analyzing gut microbiome samples from infants to gather data on their growth and health.

Why it matters

Potential benefit: If successful, this research could lead to new strategies for preventing obesity in infants and young children.

How similar studies have gone: Previous research has shown promising results in understanding the role of gut microbiome and sleep in childhood obesity, but this specific interaction is relatively novel.

Where this research is happening

  • Arizona State University-Tempe Campus
    Tempe, United States
    Active

Researchers

  • Principal investigator: Petrov, Megan Elise — Arizona State University-Tempe Campus
  • Study coordinator: Petrov, Megan Elise

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.