How sleep duration affects immune balance in urban children with asthma
Impact of Sleep Duration on Immune Balance in Urban Children with Asthma
This study is looking at how the amount of sleep urban kids with asthma get affects their immune system and asthma symptoms, and it will involve 204 children aged 8-9 trying out different sleep patterns over four weeks to see if better sleep can help them feel better.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Rhode Island Hospital NIH-funded |
| Lab location | 1 site (Providence, United States) |
| Project ID | NIH-11161838 on NIH RePORTER |
What this research studies
This research investigates the relationship between sleep duration and immune function in urban children suffering from asthma. It focuses on how short sleep, often caused by environmental factors, may lead to an imbalance in immune responses, particularly in allergic asthma. The study will enroll 204 children aged 8-9 years with persistent allergic asthma and will involve a 4-week experimental protocol where participants will experience different sleep conditions to assess the impact on their immune health and asthma symptoms. By understanding this connection, the research aims to identify sleep duration as a modifiable factor in asthma management.
Who could benefit from this research
Good fit: Ideal candidates for this research are urban children aged 8-9 years who have persistent allergic asthma and currently experience adequate sleep duration.
Not a fit: Patients who do not have asthma or are outside the age range of 8-9 years may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved asthma management strategies by highlighting the importance of adequate sleep for immune balance in children.
How similar studies have performed: Previous studies in healthy adults have shown that sleep duration can significantly affect immune responses, suggesting potential for success in this similar pediatric population.
Where this research is happening
Providence, United States
- Rhode Island Hospital — Providence, United States (Active)
Researchers
- Principal investigator: Koinis Mitchell, Daphne — Rhode Island Hospital
- Study coordinator: Koinis Mitchell, Daphne
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.